Desired Patient Outcomes
<aside>
😃 Achieve complete or near complete symptom relief
</aside>
<aside>
👨👩👧 Restore quality of life
</aside>
<aside>
🩺 No concerning side effects
</aside>
<aside>
🏋🏻 Optimising lifestyle for overall health - Exercise, nutrition, sleep
</aside>
Goal Hormone Levels:
Free Testosterone:
- Between 400-800 pmol/L depending on symptom relief and clinical presentation, at trough (when due for injection)
- Individuals have varying degrees of androgen sensitivity and may need to be at higher end of range for complete symptom relief, or vice versa
- Some patients feel better at the lower side of the scale, more testosterone does not always equal more notable symptom relief
Estrogen (E2)
- Goal is between 70 - 200 pmol/L
- Some individuals can be higher with no negative estrogenic side effects and feel great, but some men will see reversal of treatment benefits, and or negative side effects
- Why high estrogen (excess aromatisation) in some patients? Excess body fat, liver issues, insulin resistance, undiagnosed sleep apnea, lack of cardiovascular exercise or genetic causes
- How to lower estrogen? Address root cause of excess aromatisation (listed above) and or commence an aromatase inhibitor.